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MyClyns LITERATURE REFERENCES
Independent Laboratory Tests Microcyn® Technology


The following is a list of published studies regarding the antimicrobial properties of Microcyn®, the technology utilized in MyClyns™ :
(* these studies are available for download)

Landa-Solis, C., Ganzalez-Espinosa, D., Guzman-Soriano B., et.al. Microcyn®: a novel super-oxidized water with neutral pH and disinfectant activity. J. Hosp Infect. 2005;61(4):291-299.

Tanaka, H., Hirakata, Y., Kaku, M., et al. Antimicrobial activity of super-oxidized water. J Hosp Infect. 1996;34(1):43-49.

Dalla Paola, L., Brocco, E., Senesi, A., Ninkovic, S., Mericvo, M., De Vido, D. Use of Dermacyn®, a new antiseptic for the local treatment of diabetic foot ulcers. J Wound Healing. 2005;2:201.

Altamirano, A. Reducing Bacterial Infectious Complications from Burn Wounds. A look at the use of Oculus Microcyn® to treat wounds in Mexico. Wounds. 2006;Supplement:17-19.

Gutierrez, A., Super-Oxidized Water Kills Bacteria; Demonstrates Potential for Healing, Dermatology Times. 26(6), June 2005.

Nakae, H., Inaba, H. Effectiveness of electrolyzed oxidized water irrigation in a burn-wound infection model. J. Trauma. 2000;49(3):511-514.

*Taketa, M., Gutierrrez, A.A., Thatcher, E. The Anti-Viral Efficacy of a New Super-Oxidized Solution. Submitted for publication. 2007.

*Thatcher, E., Gutierrrez, A.A. The Anti-Bacterial Efficacy of a New Super-Oxidized Solution. Submitted for publication. 2007.

le Duc, Q., Breetveld, M., Middelkoop, E., Scheper, R.J., Ulrich, M.M.W., Gibbs, S. A Cytotoxic Analysis of Antiseptic Medication on Skin Substitutes and Autograft. British Journal of Dermatology. March 2007.

Davis, J.M., Maki, J., Bahcall, J.K. An In Vitro Comparison of the Antimicrobial Effects of Various Endodontic Medicaments on Enterococcus faecalis. Journal of Endodontics. 33(5), May 2007.

Zahumensky, E. Infections and diabetic foot syndrome in field practice. Vnitr Lek. 2006;52:411-416.

Veverkova, L., Jedlicka, V., Vesely, M., Tejkalova, R., Zabranska, S., Capov, I., Votava, M.
Methicilin-resistent Staphylococcus aureus - problem in health care. J Wound Healing. 2005, 2:201-202.

Reprints of these studies are available upon request.


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The following is a list of published studies regarding the wound care properties of Microcyn®, the technology utilized in MyClyns™ :

Piagessi, A., MD. Efficacy and Safety of a Novel, Super-Oxidized Solution in Managing Post-Surgical Lesions of the Diabetic Foot. Diabetic Foot Global Conference 2008. March 13-15, 2008. Los Angeles, CA.

Suri, A., DPM. The Effect of Neutral-pH Super-Oxidized Solution for the Treatment of Infected Diabetic Foot Wounds. Diabetic Foot Global Conference 2008. March 13-15, 2008. Los Angeles, CA.

Frykberg, R., DPM, MPH. Wound Healing in Chronic Lower Extremity Wounds Comparing Super-Oxidized Solution vs. Saline. Diabetic Foot Global Conference 2008. March 13-15, 2008. Los Angeles, CA.

Allie, D.E. Super-Oxidized Dermacyn® in Lower-Extremity Wounds. Wounds. 2006;Supplement:3-6.

Gutierrez, A. The Science Behind Stable, Super-Oxidized Water. Wounds. 2006;Supplement:7-10.

Wolvos, T.A. Advanced Wound Care with Stable, Super-Oxidized Water. Wounds. 2006;Supplement:11-13.

Paola, L.D. Treating Diabetic Foot Ulcers with Super-Oxidized Water. Wounds. 2006;Supplement:14-16.

Paola, L.D., Brocco, E., Senesi, A., Mericvo, M., De Vido, D., Assaloni, R., DaRos, R. Super-oxidized Solution (SOS) Therapy for Infected Diabetic Foot Ulcers. Wounds. 2006, 18(9), 262-270.

Bongiovanni, C.M., Superoxidized Water Improves Wound Care Outcomes in Diabetic Patients. Diabetic Microvascular Complications Today. 2006; May/June:11-14.

Bongiovanni, C.M., Nonsurgical Management of Chronic Wounds in Patients with Diabetes. The Journal for Vascular Ultrasound. 30(4):215-218, 2006.

Gonzalez-Espinosa, D., Perez-Romano, L., Guzman-Soriano, B., Arias, E., Bongiovanni, C.M., Gutierrez, A.A. Effects of pH-neutral, Super-Oxidized Solution on Human Dermal Fibroblasts in-vitro. International Wound Journal. Submitted for publication. 2007.

Goretti, C., Mazzurco, S., Nobili, L.A., Macchiarini, S., Tedeschi,A., Palumbo,F., Scatena,A., Rizzo,L., Piaggesi, A. Clinical Outcomes of Wide Postsurgical Lesions in the Infected Diabetic Foot Managed With 2 Different Local Treatment Regimes Compared Using a Quasi-Experimental Study Design: A Preliminary Communication. Lower Extremity Wounds. 6(1), 2007, 22-27.

Paola, L.D., Faglia, E. Treatment of Diabetic Foot Ulcer: An Overview Strategies for Clinical Approach. Current Diabetes Reviews. 2006, 2, 431-447.

Medina-Tamayo, J., Sánchez-Miranda, E., Balleza-Tapia, H., López, X., Cid, M.E., González-Espinosa, D., Gutiérrez, A.A., González-Espinosa, C. Super-oxidized Solution Inhibits IgE-antigen-induced Degranulation and Cytokine Release in Mast Cells. Submitted for Publication, 2007.

Yahagi, N., Kono, M., Kitahara, M., Ohmura, A., Sumita, O., Hashimoto, T., Hori, K., Ning-Juan, C., Woodson, P., Kubota, S., Murakami, A., Takamoto, S. Effect of electrolyzed water on wound healing. Artif Organs. 2000, 24:984-987.

Reprints of these studies are available upon request.


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The following study posters were presented at the 47th Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) regarding the oxychlorine solution contained in MyClyns™.

These posters are available for downloading by clicking on the listings below:

1. Taketa-Graham, M., Gutierrez, A.A., Thatcher, E. The Anti-Viral Efficacy of a New Super-Oxidized Solution.

2. Thatcher, E., Gutierrez, A.A. The Anti-Bacterial Efficacy of a New Super-Oxidized Solution.

3. Dardine, J., Martinez, C., Thatcher, E. Activity of a pH Neutral Super-Oxidized Solution Against Bacteria Selected for Sodium Hypochlorite Resistance.

Click here to download our product literature, training guide, indpendent laboratory data, and other useful information regarding MyClyns.

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